DEVELOPMENT AND CHARACTERIZATION OF REVERSE GENETICS SYSTEMS OF FELINE INFECTIOUS PERITONITIS VIRUS FOR ANTIVIRAL RESEARCH

Development and characterization of reverse genetics systems of feline infectious peritonitis virus for antiviral research

Abstract Feline infectious peritonitis (FIP) is a lethal, immune-mediated disease in cats caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV).In contrast to feline enteric coronavirus (FECV), which exclusively infects enterocytes and causes diarrhea, FIPV specifically targets macrophages, resulting in the Cr

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Eugenol: In Vitro and In Ovo Assessment to Explore Cytotoxic Effects on Osteosarcoma and Oropharyngeal Cancer Cells

Cancer is a significant health problem worldwide; consequently, new therapeutic alternatives are being investigated, including those found in Perfume the vegetable kingdom.Eugenol (Eug) has attracted attention for its therapeutic properties, especially in stomatology.The purpose of this study was to investigate the cytotoxicity of Eug, in vitro, on

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